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Interogenesis Designs
Human Factors Design Thinking & Productivity
A Translational Astrobiology Initiative
This training program presents an innovative human factors design thinking and productivity experience.
Based upon a novel model of the progression of origin of life chemistry and the conservation of the protocell structure, an innovative anatomy and physiology model is presented. All aspects of biological research, astrobiology, and specifically origin of life astromaterial analysis benefit from this approach. . The experiential curriculum achieves two goals simultaneously:
Index Links for this Webpage:
Issues and Goals of the Astrobiology Decadal Survey 2023-2032
Origin of Life & Protocell Informed Innovation
Innovative Transdisciplinary Scoping Review
Concept Gap in Basic Biological and Physical Sciences
Protocell Based Novel Unit of Measure
Protocell Informed Model of Anatomy and Physiology
Refining the Bilateral Classification of Human Anatomy
Expanded Concept of Information Theory in Astrobiology
Protocell Scaling Application Model; Proposed Applications and Benefits
Summary
The research and applications of Interogenesis Designs address two goals:
1. The discovery and efficiency of scientists.
Interogenesis Designs has developed a human factors methodology, arising from healthcare and anatomy and physiology principles, that support astrobilologists and space scientists to:
1. Process large quantities of fragmented data and organize into more coherent systems to support decision making.
See: Human Factors Design Thinking & Productivity
Astrobiology Decadal Survey (2023-2032)
Building upon stated goals and issues within the recent Astrobiology Decadal Survey (2023-2032), Interogenesis Designs:
Our main 'society facing' project integrates NASA funded research in the origin of life and protocell development with our proprietary research into a health and wellness application. This initiative integrates astrobiology into the broader biological, health and medical sciences to help solve costly social health and wellness challenges.
A 'Protocell Scaling Application Model' is proposed that translates undervalued primordial elements of the protocell structure and mechanisms of action into a wide range of applications to benefit society.
Other applications are described below and on these webpages. Our initiatives demonstrates the value of astrobiology to produce societal benefits and economic impact.
For example, Based upon the transdiciplinary scoping review, which included insights into economic, healthcare and astrobiology, the following project is is in a visioning and conceptualization stage.
NASA Astrobiology Outreach Pavilion
Los Angeles 2028 Summer Olympics and Paralympics Games
It will be proposed to NASA to establish an outreach pavilion at the Los Angeles 2028 Summer Olympics and Paralympics. The foundation science that substantiates this investment is included on these webpages. The core foundation is based upon translating the principles of the protocell and preceding origin of life stages into applications oriented towards health, education, and innovation.
It is the conclusion of this research that the magnitude of the innovations that have been identified warrant a bold proposal of this magnitude.
To be informed of future development of our projects.
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Issues and Goals from the Astrobiology Decadal Survey 2023-2032
The conclusions, innovations and proposals on these pages directly address stated issues and goals of the Astrobiology Decadal Survey:
Origins, Worlds, and Life: A Decadal Strategy for Planetary Science and Astrobiology 2023-2032 (2023).
Including these statements (Italics and emphasis added):
Chapter 14, Question 11: Search for Life Elsewhere, p. 367-368;
Four hundred years after Galileo revolutionized our understanding of our place in the universe, ours could realistically be the generation that triggers another scientific revolution, this time in biology.
Our understanding of Earth life provides a starting point for investigation (Question 9, Chapter 12), contrasting the signatures of life on Earth with the prebiotic/abiotic chemistry of primitive bodies.
Expanding the search (for life) to include the possibility of nonterran life (i.e., life “not as we know it”) (NRC 2007) requires further technical and conceptual maturation, including advances in statistical methods, scaling laws, information theory, and probabilistic approaches.
Chapter 12, Question 9: Insights from Terrestrial Life, P. 209 - 310
It is important to note that our understanding of life on Earth continues to evolve rapidly thanks to paradigm-changing discoveries of life’s ability to survive, and even thrive, in multi-extreme environments. … This evolving knowledge of Earth’s biosphere, from its origins to its current state, directly informs and influences the search for life elsewhere.
Insights gained from the biochemistry, structure, and physiology of terrestrial organisms—and how they have evolved through deep time—are the basis to develop comprehensive frameworks to search for evidence of life on other worlds.
Origin of Life & Protocell Informed Innovation
These pages contain origin of life and protocell informed research that is proposed to contribute to conceptual maturation of the framework for astrobiology origin of life research. Specifically by improving the understanding of human living systems, specifically for astrobiologists, to support them to expand their world view and practical skill set of measurement and inquiry as they explore terrestrial material and extrapolate to the potential of life in nonterran environments.
The proposed nontraditional research is a measurement and inquiry tactic and framework which includes:
Clarifying the lens, and expanding the degrees of freedom of measurement and inquiry of the human astrobilogy researcher
Support the exploration of extreme unknowns, such as searching for bio signatures of life ‘as we don’t know it’ in astromaterial samples.
The expansive world view proposed in this research supports the robust holistic, transdisciplinary nature of astrobiology.
The research conclusions propose a human factors, anatomy and physiology initiative with notable societal benefits.
The following themes on this webpage and across this website are proposed to expand the inquiry and measurement tool kit of the astrobiology researcher. This supports the researcher to better understand life on earth and thereby contribute to the framework to understand nonterran potential life.
A Model Protocell
Credit: Janet Iwasa, Szostak Laboratory, Harvard Medical School and Massachusetts General Hospital
Innovative Transdisciplinary Scoping Review
Based upon a novel transdisciplinary scoping review, our research concludes that current astrobiology research in origin of life/protocell development can be applied to fill a notable gap in the progression of scientific knowledge over the past 500 years in Euro-American culture.
This includes Identifying:
See: Systemic Productivity, An Informal Scoping Review
Concept Gap in Basic Biological and Physical Sciences
A detail assessment of biological and physical science reveal that a specific, common, real world phenomenon is poorly described within existing academic concepts. These phenomenon relate to the principles of ‘work’, ‘measurement’ and ‘communication’. The research concludes that this concept contributes to notable societal cost. Thus repairing the concept gap and promoting its benefits is highly beneficial to society
See: Interogenesis - The Principle Protocell Based Novel Unit of Measure
The concept gap between physical and biological sciences can be repaired, in part, by establishing a new, protocell informed biological unit of measurement. This proposed unit of measure reflects real world phenomenon. The unit of measurement is highly informed by the structures and functions of the protocell. It is a practical assessment and educational tool that promotes a skill set and promotes societal benefit.
See: Interogenesis - The Principle
Protocell Informed Model of Anatomy and Physiology:
Refining the Bilateral Classification of Human Anatomy A 300 – 700 Year Historic Scientific Revision Implications for the Societal Benefits and Economic Impact of Astrobiology
Based upon the transdisciplinary Scoping Review, it is proposed that the protocell model implies that the prevailing classification of human anatomy and physiology as bilateral is inaccurate and incomplete.
The proposed new physiology model extends the bilateral classification based upon a direct observation and assessment of physical structures of the modern human.
The proposal that the bilateral classification of human anatomy is inaccurate and incomplete is not a hypothesis. The structures of the human body reveal a more complex structure than bilateral. These structures are observable. As is seen in other aspects of symmetry in biology, there are imperfections, which establish that the ‘non-bilateral’ conclusion includes an interpretation by the author.
The implications of this distinction reverberate over the past 300 to 700 years of Euro-American science, if not longer, proposing a historic revision of principles of anatomy and physiology.
It is proposed that this has significant implications for astrobiology research, especially astromaterial sample analysis.
Key point that contribute this conclusion are:
Expanded Concept of Information Theory in Astrobiology
Building upon the proposed new classification of human physiology. This protocell informed approach proposes an information/communication/signaling model built upon a broad anatomy and physiology model. For example, integrating communication and signaling that reflects the primordial protocell model and spans the central nervous system and neurology with systems biology.
It is a whole body, anatomy and physiology approach to information, communication and signaling living human biological systems. It is proposed that this expands the measurement and inquiry capacities of the astrobiology researcher.
This approach is distinctly different than the information theories of the past 70 years (Shannon and Weaver, 1948) that arose from the telecommunications industry, and are based upon information signaling in technology, i.e., non-living systems. This telecommunication based information theory approach has benefits, yet it narrows the concepts of information, communication and signaling in astrobiology.
The resulting protocell information, communication and signaling model is proposed as an integral foundation of the proposed nontraditional methodology for astrobiology research.
Protocell Scaling Application Model
Proposed Applications and Benefits
This research proposes that the protocell model establishes a framework that describes a broad array of current human societal activities. Yet, there are historic, cultural physiology and behavioral patterns, that are proposed to be inefficient because they poorly reflect the organic protocell.
This creates an opportunity to scale the structures and mechanisms of action of the protocell into applications to benefit society.
The current applications under development include:
1) A Nontraditional Research Methodology for Astrobiology
A nontraditional research methodology to increase discovery and science output in astromaterial sample analysis, with broader application to general astrobiology and general biology research. This method is based upon an innovative diversity model specific to astrobiology research.
A central goal of the nontraditional method is to assist the astrobiology researcher to clarify the deep nature of life on earth, in the human body, as a framework to measure and inquiry any terrestrial material. This is a step identified in the current Astrobiology Decadal to assist a researcher to inquire into the nature of nonterran life forms.
Two high value applications of this method are:
A) All ‘Follow the Water’ astrobiology and exoplanet research projects.
B) Astromaterial sample analysis,(Such as teh OSIRIS-REx Asteroid Sample Return Mission, and the Mars Sample Return Mission).
Broader Applications: The method can be easily translated to the broader academic and science community to achieve efficiency of academic and science output, specifically, but not exclusively related to biology.
Proposed Benefits:
- Increased speed of discovery and science output. Reducing the time line to output. - Expanded degrees of freedom for inquiry and innovation. - Increased ROI for astrobiology, sample analysis, and origin of life inquiry. - Societal benefits to healthcare, education, innovation, general productivity.
See: Methods Innovation
2) Wellness, Healthcare and Medicine Initiative
2a) Current NASA funded research in astrobiology origin of life and protocell formation can be translated into a health and wellness initiative with systemic productivity benefits. This is a health economics initiative.
2b) This initiative builds upon insights from the April 2001 National Institute of Health/ NASA Astrobiology Institute Joint Symposium.
See: The National Institutes of Health and the NASA Astrobiology Institute Joint Symposium
3) Expanding astrobiology outreach
Three outreach initiatives are in development: Infrastructure, Commercial Industry, Consumer:
3a) Infrastructure
Several infrastructure organizations have expressed preliminary curiosity and interest in this systemic productivity initiative, including:
3b) Commercial Industry
Using a technology transfer strategy that utilizes astrobiology principles and innovation, commercial industry partners have been identified to co-develop:
Employee training for health and wellness, productivity, and innovation.
3c) Consumer Utilizing an arts-science-healthcare approach, several consumer level media initiatives are in development.
Please contact:
Daniel Lappin BA, CMP
San Francisco Bay Area, CA.
Daniel (at) Interogenesis.com
415-936-9981
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